Publications

Publications 2014

 

January

Claussnitzer M, Dankel SN, Klocke B, Grallert H, Glunk V, Berulava T, Lee H, Oskolkov N, Fadista J, Ehlers K, Wahl S, Hoffmann C, Qian K, Rönn T, Riess H, Müller-Nurasyid M, Bretschneider N, Schroeder T, Skurk T, Horsthemke B; DIAGRAM+Consortium, Spieler D, Klingenspor M, Seifert M, Kern MJ, Mejhert N, Dahlman I, Hansson O, Hauck SM, Blüher M, Arner P, Groop L, Illig T, Suhre K, Hsu YH, Mellgren G, Hauner H, Laumen H. Leveraging cross-species transcription factor binding site patterns: from diabetes risk Loci to disease mechanisms. Cell. 2014 Jan 16;156(1-2):343-58.

Hasmats J, Gréen H, Orear C, Validire P, Huss M, Käller M, Lundeberg J. Assessment of whole genome amplification for sequence capture and massively parallel sequencing. PLoS One. 2014 Jan 7;9(1):e84785.

Song Y, Gyarmati P, Araújo AC, Lundeberg J, Brumer H 3rd, Ståhl PL. Visual Detection of DNA on Paper Chips. Anal Chem. 2014 Jan 17.

 

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Publications 2013

December

Kulyté A, Belarbi Y, Lorente-Cebrián S, Bambace C, Arner E, Daub CO, Hedén P, Rydén M, Mejhert N, Arner P. Additive effects of miRNAs and transcription factors on CCL2 production in human white adipose tissue. Diabetes. 2013 Dec 30.

Kulyté A, Lorente-Cebrián S, Gao H, Mejhert N, Agustsson T, Arner P, Rydén M, Dahlman I. MicroRNA profiling links miR-378 to enhanced adipocyte lipolysis in human cancer cachexia. Am J Physiol Endocrinol Metab. 2013 Dec 10.

Lazar V, Suo C, Orear C, van den Oord J, Balogh Z, Guegan J, Job B, Meurice G, Ripoche H, Calza S, Hasmats J, Lundeberg J, Lacroix L, Vielh P, Dufour F, Lehtiö J, Napieralski R, Eggermont A, Schmitt M, Cadranel J, Besse B, Girard P, Blackhall F, Validire P, Soria JC, Dessen P, Hansson J, Pawitan Y. Integrated molecular portrait of non-small cell lung cancers. BMC Med Genomics. 2013 Dec 3;6:53.

Falkenius J, Lundeberg J, Johansson H, Tuominen R, Frostvik-Stolt M, Hansson J, Egyhazi Brage S. High expression of glycolytic and pigment proteins is associated with worse clinical outcome in stage III melanoma. Melanoma Res. 2013 Dec;23(6):452-60.

He P, Aldahan A, Possnert G, Hou X. Temporal variation of iodine isotopes in the North Sea. Environ Sci Technol. 2013 Dec 20.

November

Lorente-Cebrián S, Decaunes P, Dungner E, Bouloumié A, Arner P, Dahlman I. Allograft inflammatory factor 1 (AIF-1) is a new human adipokine involved in adipose inflammation in obese women. BMC Endocr Disord. 2013 Nov 25;13(1):54.

Arner E, Arner P. Health and obesity: not just skin deep. Science. 2013 Nov 1;342(6158):558-9.

Sabelström H, Stenudd M, Réu P, Dias DO, Elfineh M, Zdunek S, Damberg P, Göritz C, Frisén J. Resident neural stem cells restrict tissue damage and neuronal loss after spinal cord injury in mice. Science. 2013 Nov 1;342(6158):637-40.

He P, Hou X, Aldahan A, Possnert G, Yi P. Iodine isotopes species fingerprinting environmental conditions in surface water along the northeastern Atlantic Ocean. Sci Rep. 2013 Nov 28;3:2685.

October

Sell H, Blüher M, Klöting N, Schlich R, Willems M, Ruppe F, Knoefel WT, Dietrich A, Fielding BA, Arner P, Frayn KN, Eckel J. Adipose dipeptidyl peptidase-4 and obesity: correlation with insulin resistance and depot-specific release from adipose tissue in vivo and in vitro. Diabetes Care. 2013 Dec;36(12):4083-90. doi: 10.2337/dc13-0496. Epub 2013 Oct 15.

Jiang LQ, Franck N, Egan B, Sjögren RJ, Katayama M, Duque-Guimaraes D, Arner P, Zierath JR, Krook A. Autocrine role of interleukin-13 on skeletal muscle glucose metabolism in type 2 diabetic patients involves microRNA let-7. Am J Physiol Endocrinol Metab. 2013 Dec 1;305(11):E1359-66. doi: 10.1152/ajpendo.00236.2013. Epub 2013 Oct 8.

August

Watanabe H, Fitting S, Hussain MZ, Kononenko O, Iatsyshyna A, Yoshitake T, Kehr J, Alkass K, Druid H, Wadensten H, Andren PE, Nylander I, Wedell DH, Krishtal O, Hauser KF, Nyberg F, Karpyak VM, Yakovleva T, Bakalkin G. Asymmetry of the Endogenous Opioid System in the Human Anterior Cingulate: a Putative Molecular Basis for Lateralization of Emotions and Pain. Cereb Cortex. 2013 Aug 19.

Yi P, Chen XG, Bao DX, Qian RZ, Aldahan A, Tian FY, Possnert G, Bryhn AC, Gu TF, Hou XL, He P, Yu ZB, Wang B. Model simulation of inflow water to the Baltic Sea based on ¹²⁹I. Appl Radiat Isot. 2013 Dec;82:223-31. doi: 10.1016/j.apradiso.2013.07.034. Epub 2013 Aug 12.

July

Rydén M, Andersson DP, Bernard S, Spalding K, Arner P. Adipocyte triglyceride turnover and lipolysis in lean and overweight subjects. J Lipid Res. 2013 Oct;54(10):2909-13. doi: 10.1194/jlr.M040345. Epub 2013 Jul 30.

Alkass K, Saitoh H, Buchholz BA, Bernard S, Holmlund G, Senn DR, Spalding KL, Druid H. Analysis of radiocarbon, stable isotopes and DNA in teeth to facilitate identification of unknown decedents. PLoS One. 2013 Jul 29;8(7):e69597.

Kronstrand R, Roman M, Dahlgren M, Thelander G, Wikström M, Druid H. A cluster of deaths involving 5-(2-aminopropyl)indole (5-IT). J Anal Toxicol. 2013 Oct;37(8):542-6. doi: 10.1093/jat/bkt058. Epub 2013 Jul 9.

June

Pettersson AM, Stenson BM, Lorente-Cebrián S, Andersson DP, Mejhert N, Krätzel J, Aström G, Dahlman I, Chibalin AV, Arner P, Laurencikiene J. LXR is a negative regulator of glucose uptake in human adipocytes. Diabetologia. 2013 Sep;56(9):2044-54. doi: 10.1007/s00125-013-2954-5. Epub 2013 Jun 15.

Spalding KL, Bergmann O, Alkass K, Bernard S, Salehpour M, Huttner HB, Boström E, Westerlund I, Vial C, Buchholz BA, Possnert G, Mash DC, Druid H, Frisén J. Dynamics of hippocampal neurogenesis in adult humans. Cell. 2013 Jun 6;153(6):1219-27.

Persson A, Eilers G, Ryderfors L, Mukhtar E, Possnert G, Salehpour M. Evaluation of intracavity optogalvanic spectroscopy for radiocarbon measurements. Anal Chem. 2013 Jul 16;85(14):6790-8. doi: 10.1021/ac400905n. Epub 2013 Jun 24.

May

Andersson DP, Wahrenberg H, Toft E, Qvisth V, Löfgren P, Hertel K, Leijonhufvud BM, Thorell A, Näslund E, Arner P. Waist circumference to assess reversal of insulin resistance following weight reduction after bariatric surgery: cohort and cross-sectional studies. Int J Obes (Lond). 2013 May 24.

Stocks T, Taylor MA, Angquist L, Macdonald IA, Arner P, Holst C, Oppert JM, Martinez JA, Rössner S, Polak J, Langin D, Saris WH, Astrup A, Sørensen TI. Change in proportional protein intake in a 10-week energy-restricted low- or high-fat diet, in relation to changes in body size and metabolic factors. Obes Facts. 2013;6(3):217-27. doi: 10.1159/000351726. Epub 2013 May 22.

Claesson A, Druid H, Lindqvist J, Herlitz J. Cardiac disease and probable intent after drowning. Am J Emerg Med. 2013 Jul;31(7):1073-7. doi: 10.1016/j.ajem.2013.04.004. Epub 2013 May 20.

Bergmann O, Frisén J. Neuroscience. Why adults need new brain cells. Science. 2013 May 10;340(6133):695-6.

Nystedt B, Street NR, Wetterbom A, Zuccolo A, Lin YC, Scofield DG, Vezzi F, Delhomme N, Giacomello S, Alexeyenko A, Vicedomini R, Sahlin K, Sherwood E, Elfstrand M, Gramzow L, Holmberg K, Hällman J, Keech O, Klasson L, Koriabine M, Kucukoglu M, Käller M, Luthman J, Lysholm F, Niittylä T, Olson A, Rilakovic N, Ritland C, Rosselló JA, Sena J, Svensson T, Talavera-López C, Theißen G, Tuominen H, Vanneste K, Wu ZQ, Zhang B, Zerbe P, Arvestad L, Bhalerao R, Bohlmann J, Bousquet J, Garcia Gil R, Hvidsten TR, de Jong P, MacKay J, Morgante M, Ritland K, Sundberg B, Thompson SL, Van de Peer Y, Andersson B, Nilsson O, Ingvarsson PK, Lundeberg J, Jansson S. The Norway spruce genome sequence and conifer genome evolution. Nature. 2013 May 30;497(7451):579-84. doi: 10.1038/nature12211. Epub 2013 May 22.

April

Boström P, Frisén J. New cells in old hearts. N Engl J Med. 2013 Apr 4;368(14):1358-60.

March

Arner P, Andersson DP, Thörne A, Wirén M, Hoffstedt J, Näslund E, Thorell A, Rydén M. Variations in the size of the major omentum are primarily determined by fat cell number. J Clin Endocrinol Metab. 2013 May;98(5):E897-901. doi: 10.1210/jc.2012-4106. Epub 2013 Mar 29.

Strodthoff D, Lundberg AM, Agardh HE, Ketelhuth DF, Paulsson-Berne G, Arner P, Hansson GK, Gerdes N. Lack of invariant natural killer T cells affects lipid metabolism in adipose tissue of diet-induced obese mice. Arterioscler Thromb Vasc Biol. 2013 Jun;33(6):1189-96. doi: 10.1161/ATVBAHA.112.301105. Epub 2013 Mar 21.

Lundin S, Gruselius J, Nystedt B, Lexow P, Käller M, Lundeberg J. Hierarchical molecular tagging to resolve long continuous sequences by massively parallel sequencing. Sci Rep. 2013;3:1186.

Costea PI, Lundeberg J, Akan P. TagGD: fast and accurate software for DNA Tag generation and demultiplexing. PLoS One. 2013;8(3):e57521. doi: 10.1371/journal.pone.0057521. Epub 2013 Mar 4.

February

Girousse A, Tavernier G, Valle C, Moro C, Mejhert N, Dinel AL, Houssier M, Roussel B, Besse-Patin A, Combes M, Mir L, Monbrun L, Bézaire V, Prunet-Marcassus B, Waget A, Vila I, Caspar-Bauguil S, Louche K, Marques MA, Mairal A, Renoud ML, Galitzky J, Holm C, Mouisel E, Thalamas C, Viguerie N, Sulpice T, Burcelin R, Arner P, Langin D. Partial inhibition of adipose tissue lipolysis improves glucose metabolism and insulin sensitivity without alteration of fat mass. PLoS Biol. 2013 Feb;11(2):e1001485. doi: 10.1371/journal.pbio.1001485. Epub 2013 Feb 19.

Uusitupa M, Hermansen K, Savolainen MJ, Schwab U, Kolehmainen M, Brader L, Mortensen LS, Cloetens L, Johansson-Persson A, Onning G, Landin-Olsson M, Herzig KH, Hukkanen J, Rosqvist F, Iggman D, Paananen J, Pulkki KJ, Siloaho M, Dragsted L, Barri T, Overvad K, Bach Knudsen KE, Hedemann MS, Arner P, Dahlman I, Borge G, Baardseth P, Ulven SM, Gunnarsdottir I, Jónsdóttir S, Thorsdottir I, Orešič M, Poutanen KS, Risérus U, Akesson B. Effects of an isocaloric healthy Nordic diet on insulin sensitivity, lipid profile and inflammation markers in metabolic syndrome - A randomized study (SYSDIET). J Intern Med. 2013 Feb 7. doi: 10.1111/joim.12044.

Yi P, Possnert G, Aldahan A, Hou XL, Bryhn AC, He P. (129)I in the Baltic Proper and Bothnian Sea: application for estimation of water exchange and environmental impact. J Environ Radioact. 2013 Feb 21;120C:64-72. doi: 10.1016/j.jenvrad.2013.01.009.

January

Bambace C, Dahlman I, Arner P, Kulyté A. NPC1 in human white adipose tissue and obesity. BMC Endocr Disord. 2013 Jan 30;13:5. doi: 10.1186/1472-6823-13-5.

Sabelström H, Stenudd M, Frisén J. Neural stem cells in the adult spinal cord. Exp Neurol. 2013 Jan 30. doi:pii: S0014-4886(13)00039-3. 10.1016/j.expneurol.2013.01.026.

Gioti A, Nystedt B, Li W, Xu J, Andersson A, Averette AF, Münch K, Wang X, Kappauf C, Kingsbury JM, Kraak B, Walker LA, Johansson HJ, Holm T, Lehtiö J, Stajich JE, Mieczkowski P, Kahmann R, Kennell JC, Cardenas ME, Lundeberg J, Saunders CW, Boekhout T, Dawson TL, Munro CA, de Groot PW, Butler G, Heitman J, Scheynius A. Genomic Insights into the Atopic Eczema-Associated Skin Commensal Yeast Malassezia sympodialis. MBio. 2013 Jan 22;4(1). doi:pii: e00572-12. 10.1128/mBio.00572-12.

Höiom V, Edsgärd D, Helgadottir H, Eriksson H, All-Ericsson C, Tuominen R, Ivanova I, Lundeberg J, Emanuelsson O, Hansson J. Hereditary uveal melanoma: A report of a germline mutation in BAP1. Genes Chromosomes Cancer. 2013 Apr;52(4):378-84. doi: 10.1002/gcc.22035. Epub 2013 Jan 23.

NEEM community members. Eemian interglacial reconstructed from a Greenland folded ice core. Nature. 2013 Jan 24;493(7433):489-94. doi: 10.1038/nature11789.

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Publications 2012

December

Frayn K, Bernard S, Spalding K, Arner P. Adipocyte triglyceride turnover is independently associated with atherogenic dyslipidemia. J Am Heart Assoc. 2012 Dec;1(6):e003467. doi: 10.1161/JAHA.112.003467. Epub 2012 Dec 19.

November

Akan P, Alexeyenko A, Costea PI, Hedberg L, Solnestam BW, Lundin S, Hällman J, Lundberg E, Uhlén M, Lundeberg J. Comprehensive analysis of the genome transcriptome and proteome landscapes of three tumor cell lines. Genome Med. 2012 Nov 18;4(11):86.

October

Yi P, Aldahan A, Possnert G, Hou XL, Hansen V, Wang B. (127)I and (129)i species and transformation in the baltic proper, kattegat, and skagerrak basins. Environ Sci Technol. 2012 Oct 16;46(20):10948-56. doi: 10.1021/es301979r. Epub 2012 Oct 5.

Cohen E, Lacombe-Duncan A, Spalding K, Macinnis J, Nicholas D, Narayanan UG, Gordon M, Margolis I, Friedman JN. Integrated complex care coordination for children with medical complexity: A mixed-methods evaluation of tertiary care-community collaboration. BMC Health Serv Res. 2012 Oct 23;12(1):366.

Jones-Jordan LA, Sinnott LT, Cotter SA, Kleinstein RN, Manny RE, Mutti DO, Twelker JD, Zadnik K; CLEERE Study Group. Time outdoors, visual activity, and myopia progression in juvenile-onset myopes. Invest Ophthalmol Vis Sci. 2012 Oct 1;53(11):7169-75. doi: 10.1167/iovs.11-8336.

Frisén J. [2012 Nobel Prize in Physiology or Medicine. Nobel Prize for a life return ticket]. Lakartidningen. 2012 Oct 10-16;109(41):1814.

Solnestam BW, Stranneheim H, Hällman J, Käller M, Lundberg E, Lundeberg J, Akan P. Comparison of total and cytoplasmic mRNA reveals global regulation by nuclear retention and miRNAs. BMC Genomics. 2012 Oct 30;13:574. doi: 10.1186/1471-2164-13-574.

September

Sahlin K, Street N, Lundeberg J, Arvestad L. Improved gap size estimation for scaffolding algorithms. Bioinformatics. 2012 Sep 1;28(17):2215-22.

Davanian H, Stranneheim H, Båge T, Lagervall M, Jansson L, Lundeberg J, Yucel-Lindberg T. Gene expression profiles in paired gingival biopsies from periodontitis-affected and healthy tissues revealed by massively parallel sequencing. PLoS One. 2012;7(9):e46440. doi: 10.1371/journal.pone.0046440. Epub 2012 Sep 28.

Linnarsson MK, Hallén A, Åström J, Primetzhofer D, Legendre S, Possnert G. New beam line for time-of-flight medium energy ion scattering with large area position sensitive detector. Rev Sci Instrum. 2012 Sep;83(9):095107.

Chell JM, Frisén J. Noisy neurons keep neural stem cells quiet. Cell Stem Cell. 2012 Sep 7;11(3):282-4.

Speller CF, Spalding KL, Buchholz BA, Hildebrand D, Moore J, Mathewes R, Skinner MF, Yang DY. Personal identification of cold case remains through combined contribution from anthropological, mtDNA, and bomb-pulse dating analyses. J Forensic Sci. 2012 Sep;57(5):1354-60.

August

Stranneheim H, Lundeberg J. Stepping stones in DNA sequencing. Biotechnol J. 2012 Sep;7(9):1063-73. doi: 10.1002/biot.201200153. Epub 2012 Aug 8.

Stocks T, Angquist L, Banasik K, Harder MN, Taylor MA, Hager J, Arner P, Oppert JM, Martinez JA, Polak J, Rousseau F, Langin D, Rössner S, Holst C, MacDonald IA, Kamatani Y, Pfeiffer AF, Kunesova M, Saris WH, Hansen T, Pedersen O, Astrup A, Sørensen TI. TFAP2B influences the effect of dietary fat on weight loss under energy restriction. PLoS One. 2012;7(8):e43212. doi: 10.1371/journal.pone.0043212. Epub 2012 Aug 27.

July

Hasmats J, Green H, Solnestam BW, Zajac P, Huss M, Orear C, Validire P, Bjursell M, Lundeberg J. Validation of whole genome amplification for analysis of the p53 tumor suppressor gene in limited amounts of tumor samples. Biochem Biophys Res Commun. 2012 Aug 24;425(2):379-83. doi: 10.1016/j.bbrc.2012.07.101. Epub 2012 Jul 27.

Hasmats J, Kupershmidt I, Rodríguez-Antona C, Su QJ, Khan MS, Jara C, Mielgo X, Lundeberg J, Green H. Identification of candidate SNPs for drug induced toxicity from differentially expressed genes in associated tissues. Gene. 2012 Sep 10;506(1):62-8. doi: 10.1016/j.gene.2012.06.053. Epub 2012 Jul 1.

June

Arner E, Mejhert N, Kulyté A, Balwierz PJ, Pachkov M, Cormont M, Lorente-Cebrián S, Ehrlund A, Laurencikiene J, Hedén P, Dahlman-Wright K, Tanti JF, Hayashizaki Y, Rydén M, Dahlman I, van Nimwegen E, Daub CO, Arner P. Adipose tissue microRNAs as regulators of CCL2 production in human obesity. Diabetes. 2012 Aug;61(8):1986-93. Epub 2012 Jun 11.

Göritz C, Frisén J. Neural stem cells and neurogenesis in the adult. Cell Stem Cell. 2012 Jun 14;10(6):657-9.

May

Dahlman I, Elsen M, Tennagels N, Korn M, Brockmann B, Sell H, Eckel J, Arner P. Functional annotation of the human fat cell secretome. Arch Physiol Biochem. 2012 Jul;118(3):84-91. doi: 10.3109/13813455.2012.685745. Epub 2012 May 23.

Bergmann O, Liebl J, Bernard S, Alkass K, Yeung MS, Steier P, Kutschera W, Johnson L, Landén M, Druid H, Spalding KL, Frisén J. The age of olfactory bulb neurons in humans. Neuron. 2012 May 24;74(4):634-9.

Seldén T, Ahlner J, Druid H, Kronstrand R. Toxicological and pathological findings in a series of buprenorphine related deaths. Possible risk factors for fatal outcome. Forensic Sci Int. 2012 Jul 10;220(1-3):284-90. Epub 2012 May 6.

April

Bjermo H, Iggman D, Kullberg J, Dahlman I, Johansson L, Persson L, Berglund J, Pulkki K, Basu S, Uusitupa M, Rudling M, Arner P, Cederholm T, Ahlström H, Risérus U. Effects of n-6 PUFAs compared with SFAs on liver fat, lipoproteins, and inflammation in abdominal obesity: a randomized controlled trial. Am J Clin Nutr. 2012 May;95(5):1003-12. Epub 2012 Apr 4.

Qiao J, Hansen V, Hou X, Aldahan A, Possnert G. Speciation analysis of ¹²⁹I, ¹³⁷Cs, ²³²Th, ²³⁸U, ²³⁹Pu and ²⁴⁰Pu in environmental soil and sediment. Appl Radiat Isot. 2012 Aug;70(8):1698-708. doi: 10.1016/j.apradiso.2012.04.006. Epub 2012 Apr 16.

March

Ståhl PL, Lundeberg J. Toward the single-hour high-quality genome. Annu Rev Biochem. 2012;81:359-78. Epub 2012 Mar 20. Review.

Araújo AC, Song Y, Lundeberg J, Ståhl PL, Brumer H 3rd. Activated paper surfaces for the rapid hybridization of DNA through capillary transport. Anal Chem. 2012 Apr 3;84(7):3311-7. Epub 2012 Mar 12.

February

January

Davanian H, Båge T, Lindberg J, Lundeberg J, Concha HQ, Sällberg Chen M, Yucel-Lindberg T. Signaling pathways involved in the regulation of TNFα-induced toll-like receptor 2 expression in human gingival fibroblasts. Cytokine. 2012 Mar;57(3):406-16. Epub 2012 Jan 5.

Messer DH, Mitchell GL, Twelker JD, Crescioni M; CLEERE Study Group. Spectacle wear in children given spectacles through a school-based program. Optom Vis Sci. 2012 Jan;89(1):19-26.

Bergmann O, Zdunek S, Frisén J, Bernard S, Druid H, Jovinge S. Cardiomyocyte renewal in humans. Circ Res. 2012 Jan 6;110(1):e17-8; author reply e19-21.

Lehto J, Räty T, Hou X, Paatero J, Aldahan A, Possnert G, Flinkman J, Kankaanpää H. Speciation of ¹²⁹I in sea, lake and rain waters. Sci Total Environ. 2012 Mar 1;419:60-7. Epub 2012 Jan 28.

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Publications 2011

December

Hansen V, Roos P, Aldahan A, Hou X, Possnert G. Partition of iodine ((129)I and (127)I) isotopes in soils and marine sediments. J Environ Radioact. 2011 Dec;102(12):1096-104.

Tjomsland V, Niklasson L, Sandström P, Borch K, Druid H, Bratthäll C, Messmer D, Larsson M, Spångeus A. The desmoplastic stroma plays an essential role in the accumulation and modulation of infiltrated immune cells in pancreatic adenocarcinoma. Clin Dev Immunol. 2011;2011:212810. Epub 2011 Dec 6.

November

Stålman A, Berglund L, Dungnerc E, Arner P, Felländer-Tsai L. Temperature-sensitive release of prostaglandin E₂ and diminished energy requirements in synovial tissue with postoperative cryotherapy: a prospective randomized study after knee arthroscopy. J Bone Joint Surg Am. 2011 Nov 2;93(21):1961-8.

October

Sandberg J, Werne B, Dessing M, Lundeberg J. Rapid flow-sorting to simultaneously resolve multiplex massively parallel sequencing products. Sci Rep. 2011;1:108. Epub 2011 Oct 6.

Andersson DP, Löfgren P, Thorell A, Arner P, Hoffstedt J. Visceral fat cell lipolysis and cardiovascular risk factors in obesity. Horm Metab Res. 2011 Oct;43(11):809-15. Epub 2011 Oct 18.

Lorente-Cebrián S, Kulyté A, Hedén P, Näslund E, Arner P, Rydén M. Relationship between site-specific HSL phosphorylation and adipocyte lipolysis in obese women. Obes Facts. 2011;4(5):365-71. Epub 2011 Oct 19.

Laurencikiene J, Skurk T, Kulyté A, Hedén P, Aström G, Sjölin E, Rydén M, Hauner H, Arner P. Regulation of lipolysis in small and large fat cells of the same subject. J Clin Endocrinol Metab. 2011 Dec;96(12):E2045-9. Epub 2011 Oct 12.

Hansen V, Yi P, Hou X, Aldahan A, Roos P, Possnert G. Iodide and iodate (129I and 127I) in surface water of the Baltic Sea, Kattegat and Skagerrak. Sci Total Environ. 2011 Dec 15;412-413:296-303. Epub 2011 Oct 26.

September

Bjursell MK, Blom HJ, Cayuela JA, Engvall ML, Lesko N, Balasubramaniam S, Brandberg G, Halldin M, Falkenberg M, Jakobs C, Smith D, Struys E, von Döbeln U, Gustafsson CM, Lundeberg J, Wedell A. Adenosine Kinase Deficiency Disrupts the Methionine Cycle and Causes Hypermethioninemia, Encephalopathy, and Abnormal Liver Function. Am J Hum Genet. 2011 Sep 28.

Arner P, Bernard S, Salehpour M, Possnert G, Liebl J, Steier P, Buchholz BA, Eriksson M, Arner E, Hauner H, Skurk T, Rydén M, Frayn KN, Spalding KL. Dynamics of human adipose lipid turnover in health and metabolic disease. Nature. 2011 Sep 25.

Salehpour M, Håkansson K, Höglund U, Grahn-Westin A, Nilsson S, Márquez M, Possnert G, Holmberg AR. Application of accelerator mass spectrometry to macromolecules: preclinical pharmacokinetic studies on a polybisphosphonate. Rapid Commun Mass Spectrom. 2011 Sep 15;25(17):2453-8.

Rydén M, Agustsson T, Andersson J, Bolinder J, Toft E, Arner P. Adipose zinc-α2-glycoprotein is a catabolic marker in cancer and noncancerous states. J Intern Med. 2012 Apr;271(4):414-20. doi: 10.1111/j.1365-2796.2011.02441.x. Epub 2011 Sep 2.

August

Rydén M, Agustsson T, Andersson J, Bolinder J, Toft E, Arner P. Adipose zinc-α2-glycoprotein is a catabolic marker in cancer and noncancerous states. J Intern Med. 2011 Aug 24.

Anveden A, Sjöholm K, Jacobson P, Palsdottir V, Walley AJ, Froguel P, Al-Daghri N, McTernan PG, Mejhert N, Arner P, Sjöström L, Carlsson LM, Svensson PA. ITIH-5 Expression in Human Adipose Tissue Is Increased in Obesity. Obesity (Silver Spring). 2011 Aug 18.

Tjomsland V, Spångeus A, Välilä J, Sandström P, Borch K, Druid H, Falkmer S, Falkmer U, Messmer D, Larsson M. Interleukin 1α sustains the expression of inflammatory factors in human pancreatic cancer microenvironment by targeting cancer-associated fibroblasts. Neoplasia. 2011 Aug;13(8):664-75.

July

Göritz C, Dias DO, Tomilin N, Barbacid M, Shupliakov O, Frisén J. A pericyte origin of spinal cord scar tissue. Science. 2011 Jul 8;333(6039):238-42.

Kulyté A, Rydén M, Mejhert N, Dungner E, Sjölin E, Arner P, Dahlman I. MTCH2 in Human White Adipose Tissue and Obesity. J Clin Endocrinol Metab. 2011 Jul 27.

Arner P. Medicine. Lipases in cachexia. Science. 2011 Jul 8;333(6039):163-4.

Lamers D, Famulla S, Wronkowitz N, Hartwig S, Lehr S, Ouwens DM, Eckardt K, Kaufman JM, Ryden M, Müller S, Hanisch FG, Ruige J, Arner P, Sell H, Eckel J. Dipeptidyl peptidase 4 is a novel adipokine potentially linking obesity to the metabolic syndrome. Diabetes. 2011 Jul;60(7):1917-25.

Taqi MM, Bazov I, Watanabe H, Sheedy D, Harper C, Alkass K, Druid H, Wentzel P, Nyberg F, Yakovleva T, Bakalkin G. Prodynorphin CpG-SNPs associated with alcohol dependence: elevated methylation in the brain of human alcoholics. Addict Biol. 2011 Jul;16(3):499-509.

Stranneheim H, Werne B, Sherwood E, Lundeberg J. Scalable transcriptome preparation for massive parallel sequencing. PLoS One. 2011;6(7):e21910. Epub 2011 Jul 7.

June

Jiao H, Arner P, Dickson SL, Vidal H, Mejhert N, Henegar C, Taube M, Hansson C, Hinney A, Galan P, Simon C, Silveira A, Benrick A, Jansson JO, Bouloumié A, Langin D, Laville M, Debard C, Axelsson T, Rydén M, Kere J, Dahlman-Wright K, Hamsten A, Clement K, Dahlman I. Genetic Association and Gene Expression Analysis Identify FGFR1 as a New Susceptibility Gene for Human Obesity. J Clin Endocrinol Metab. 2011 Jun;96(6):E962-6.

Jiao H, Arner P, Hoffstedt J, Brodin D, Dubern B, Czernichow S, van't Hooft F, Axelsson T, Pedersen O, Hansen T, Sørensen TI, Hebebrand J, Kere J, Dahlman-Wright K, Hamsten A, Clement K, Dahlman I. Genome wide association study identifies KCNMA1 contributing to human obesity. BMC Med Genomics. 2011 Jun 28;4:51.

Lorente-Cebrián S, Eriksson A, Dunlop T, Mejhert N, Dahlman I, Aström G, Sjölin E, Wåhlén K, Carlberg C, Laurencikiene J, Hedén P, Arner P, Rydén M. Differential effects of 1α,25-dihydroxycholecalciferol on MCP-1 and adiponectin production in human white adipocytes. Eur J Nutr. 2011 Jun 24.

Seldén T, Roman M, Druid H, Kronstrand R. LC-MS-MS analysis of buprenorphine and norbuprenorphine in whole blood from suspected drug users. Forensic Sci Int. 2011 Jun 15;209(1-3):113-9.

Alkass K, Buchholz BA, Druid H, Spalding KL. Analysis of 14C and 13C in teeth provides precise birth dating and clues to geographical origin. Forensic Sci Int. 2011 Jun 15;209(1-3):34-41.

Ståhl PL, Bjursell MK, Mahdessian H, Hober S, Jirström K, Lundeberg J. Translational database selection and multiplexed sequence capture for up front filtering of reliable breast cancer biomarker candidates. PLoS One. 2011;6(6):e20794. Epub 2011 Jun 15.

May

Lamers D, Famulla S, Wronkowitz N, Hartwig S, Lehr S, Ouwens DM, Eckardt K, Kaufman JM, Ryden M, Müller S, Hanisch FG, Ruige J, Arner P, Sell H, Eckel J. Dipeptidyl Peptidase 4 Is a Novel Adipokine Potentially Linking Obesity to the Metabolic Syndrome. Diabetes. 2011 May 20.

April

Berg DA, Kirkham M, Wang H, Frisén J, Simon A. Dopamine controls neurogenesis in the adult salamander midbrain in homeostasis and during regeneration of dopamine neurons. Cell Stem Cell. 2011 Apr 8;8(4):426-33.

Arner P, Arner E, Hammarstedt A, Smith U. Genetic predisposition for type 2 diabetes, but not for overweight/obesity, is associated with a restricted adipogenesis. PLoS One. 2011 Apr 12;6(4):e18284.

Hooton H, Dubern B, Henegar C, Paternoster L, Nohr EA, Alili R, Rousseau F, Pelloux V, Galan P, Hercberg S, Arner P, Sørensen TI, Clément K. Association between CST3 rs2424577 Polymorphism and Corpulence Related Phenotypes during Lifetime in Populations of European Ancestry. Obes Facts. 2011;4(2):131-44. Epub 2011 Apr 15.

Taqi MM, Bazov I, Watanabe H, Sheedy D, Harper C, Alkass K, Druid H, Wentzel P, Nyberg F, Yakovleva T, Bakalkin G. Prodynorphin CpG-SNPs associated with alcohol dependence: elevated methylation in the brain of human alcoholics. Addict Biol. 2011 Apr 26.

Borgström E, Lundin S, Lundeberg J. Large scale library generation for high throughput sequencing. PLoS One. 2011 Apr 27;6(4):e19119.

Hägg S, Salehpour M, Noori P, Lundström J, Possnert G, Takolander R, Konrad P, Rosfors S, Ruusalepp A, Skogsberg J, Tegnér J, Björkegren J. Carotid plaque age is a feature of plaque stability inversely related to levels of plasma insulin. PLoS One. 2011 Apr 7;6(4):e18248.

March

Lång P, Zakaroff-Girard A, Wåhlén K, Andersson J, Olsson T, Bambace C, Jocken J, Bouloumié A, Andersson G, Arner P. Expression and secretion of the novel adipokine tartrate-resistant acid phosphatase from adipose tissues of obese and lean women. Int J Obes (Lond). 2011 Mar 8.

Kulyté A, Pettersson AT, Antonson P, Stenson BM, Langin D, Gustafsson JA, Staels B, Rydén M, Arner P, Laurencikiene J. CIDEA interacts with liver X receptors in white fat cells. FEBS Lett. 2011 Mar 9;585(5):744-8.

Philipova T, Baryawno N, Hartmann W, Pietsch T, Druid H, Johnsen JI, Ekström TJ. Differential forms of p53 in medulloblastoma primary tumors, cell lines and xenografts. Int J Oncol. 2011 Mar;38(3):843-9.

February

Ståhl PL, Stranneheim H, Asplund A, Berglund L, Pontén F, Lundeberg J. Sun-Induced Nonsynonymous p53 Mutations Are Extensively Accumulated and Tolerated in Normal Appearing Human Skin. J Invest Dermatol. 2011 Feb;131(2):504-8.

Seldén T, Roman M, Druid H, Kronstrand R. LC-MS-MS analysis of buprenorphine and norbuprenorphine in whole blood from suspected drug users. Forensic Sci Int. 2011 Jun 15;209(1-3):113-9. Epub 2011 Feb 8.

January

Mracek T, Stephens NA, Gao D, Bao Y, Ross JA, Rydén M, Arner P, Trayhurn P, Fearon KC, Bing C. Enhanced ZAG production by subcutaneous adipose tissue is linked to weight loss in gastrointestinal cancer patients. Br J Cancer. 2011 Feb 1;104(3):441-7. Epub 2011 Jan 18.

Analysis of (14)C and (13)C in teeth provides precise birth dating and clues to geographical origin. Alkass K, Buchholz BA, Druid H, Spalding KL. Forensic Sci Int. 2011 Jan 3.

Identification of cardiomyocyte nuclei and assessment of ploidy for the analysis of cell turnover. Bergmann O, Zdunek S, Alkass K, Druid H, Bernard S, Frisén J. Exp Cell Res. 2011 Jan 15;317(2):188-94.

Alkass K, Buchholz BA, Druid H, Spalding KL. Analysis of (14)C and (13)C in teeth provides precise birth dating and clues to geographical origin. Forensic Sci Int. 2011 Jun 15;209(1-3):34-41. Epub 2011 Jan 3.

 

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Publications 2010

December

Differential forms of p53 in medulloblastoma primary tumors, cell lines and xenografts. Philipova T, Baryawno N, Hartmann W, Pietsch T, Druid H, Johnsen JI, Ekström TJ. Int J Oncol. 2010 Dec 23. doi: 10.3892/ijo.2010.884.

Nomura T, Göritz C, Catchpole T, Henkemeyer M, Frisén J. EphB signaling controls lineage plasticity of adult neural stem cell niche cells. Cell Stem Cell. 2010 Dec 3;7(6):730-43.

Pathophysiological effects and changes in potassium, ionised calcium, glucose and haemoglobin early after severe blunt chest trauma. Rocksén D, Gryth D, Druid H, Gustavsson J, Arborelius UP. Injury. 2010 Dec 2.

Lundberg E, Fagerberg L, Klevebring D, Matic I, Geiger T, Cox J, Algenäs C, Lundeberg J, Mann M, Uhlen M. Defining the transcriptome and proteome in three functionally different human cell lines. Mol Syst Biol. 2010 Dec 21;6:450.

Klevebring D, Fagerberg L, Lundberg E, Emanuelsson O, Uhlén M, Lundeberg J. Analysis of transcript and protein overlap in a human osteosarcoma cell line. BMC Genomics. 2010 Dec 2;11:684.

Yi P, Aldahan A, Hansen V, Possnert G, Hou XL. Iodine Isotopes ((129)I and (127)I) in the Baltic Proper, Kattegat, and Skagerrak Basins. Environ Sci Technol. 2010 Dec 29.

November

Sadiq MW, Salehpour M, Forsgard N, Possnert G, Hammarlund-Udenaes M. Morphine brain pharmacokinetics at very low concentrations studied with Accelerator Mass Spectrometry and Liquid Chromatography-tandem Mass Spectrometry. Drug Metab Dispos. 2010 Nov 8.

October

Effects of fluid resuscitation with hypertonic saline dextrane or Ringer's acetate after nonhemorrhagic shock caused by pulmonary contusion. Gryth D, Rocksén D, Drobin D, Druid H, Weitzberg E, Bursell J, Olsson LG, Arborelius UP. J Trauma. 2010 Oct;69(4):741-8.

Ehm O, Göritz C, Covic M, Schäffner I, Schwarz TJ, Karaca E, Kempkes B, Kremmer E, Pfrieger FW, Espinosa L, Bigas A, Giachino C, Taylor V, Frisén J, Lie DC. RBPJkappa-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus. J Neurosci. 2010 Oct 13;30(41):13794-807.

Barnabé-Heider F, Göritz C, Sabelström H, Takebayashi H, Pfrieger FW, Meletis K, Frisén J. Origin of new glial cells in intact and injured adult spinal cord. Cell Stem Cell. 2010 Oct 8;7(4):470-82.

Genander M, Frisén J. Ephrins and Eph receptors in stem cells and cancer. Curr Opin Cell Biol. 2010 Oct;22(5):611-6.

Stenson BM, Rydén M, Venteclef N, Dahlman I, Pettersson AM, Mairal A, Aström G, Blomqvist L, Wang V, Jocken JW, Clément K, Langin D, Arner P, Laurencikiene J. Liver X receptor (LXR) regulates human adipocyte lipolysis. J Biol Chem. 2011 Jan 7;286(1):370-9. Epub 2010 Oct 28.

September

 

August

Forsberg M, Carlén M, Meletis K, Yeung MS, Barnabé-Heider F, Persson MA, Aarum J, Frisén J. Efficient reprogramming of adult neural stem cells to monocytes by ectopic expression of a single gene. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14657-61.

July

Genander M, Holmberg J, Frisén J. Ephrins negatively regulate cell proliferation in the epidermis and hair follicle. Stem Cells. 2010 Jul;28(7):1196-205.

Hedskog C, Mild M, Jernberg J, Sherwood E, Bratt G, Leitner T, Lundeberg J, Andersson B, Albert J. Dynamics of HIV-1 quasispecies during antiviral treatment dissected using ultra-deep pyrosequencing. PLoS One. 2010 Jul 7;5(7):e11345.

Stranneheim H, Käller M, Allander T, Andersson B, Arvestad L, Lundeberg J. Classification of DNA sequences using Bloom filters. Bioinformatics. 2010 Jul 1;26(13):1595-600.

June

Lindberg J, Wijbrandts CA, van Baarsen LG, Nader G, Klareskog L, Catrina A, Thurlings R, Vervoordeldonk M, Lundeberg J, Tak PP. The gene expression profile in the synovium as a predictor of the clinical response to infliximab treatment in rheumatoid arthritis. PLoS One. 2010 Jun 25;5(6):e11310.

May

Dahlman I, Mejhert N, Linder K, Agustsson T, Mutch DM, Kulyte A, Isaksson B, Permert J, Petrovic N, Nedergaard J, Sjölin E, Brodin D, Clement K, Dahlman-Wright K, Rydén M, Arner P. Adipose tissue pathways involved in weight loss of cancer cachexia. Br J Cancer. 2010 May 11;102(10):1541-8.

Arner P, Spalding KL. Fat cell turnover in humans. Biochem Biophys Res Commun. 2010 May 21;396(1):101-4.

Genander M, Frisén J. Eph receptors tangled up in two: Independent control of cell positioning and proliferation. Cell Cycle. 2010 May 3;9(10).

Genander M, Holmberg J, Frisén J. Ephrins Negatively Regulate Cell Proliferation in the Epidermis and Hair Follicle. Stem Cells. 2010 May 10.

Hara Y, Nomura T, Yoshizaki K, Frisén J, Osumi N. Impaired hippocampal neurogenesis and vascular formation in ephrin-A5-deficient mice. Stem Cells. 2010 May;28(5):974-83.

Stranneheim H, Käller M, Allander T, Andersson B, Arvestad L, Lundeberg J. Classification of DNA sequences using Bloom filters. Bioinformatics. 2010 May 13.

Salehpour M, Ekblom J, Sabetsky V, Håkansson K, Possnert G. Accelerator mass spectrometry offers new opportunities for microdosing of peptide and protein pharmaceuticals. Rapid Commun Mass Spectrom. 2010 May 30;24(10):1481-9.

Buchholz BA, Spalding KL. Year of birth determination using radiocarbon dating of dental enamel. Surf Interface Anal. 2010 May 1;42(5):398-401.

April

Seidel S, Garvalov BK, Wirta V, von Stechow L, Schänzer A, Meletis K, Wolter M, Sommerlad D, Henze AT, Nistér M, Reifenberger G, Lundeberg J, Frisén J, Acker T. A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha. Brain. 2010 Apr;133(Pt 4):983-95.

Båge T, Lindberg J, Lundeberg J, Modéer T, Yucel-Lindberg T. Signal pathways JNK and NF-kappaB, identified by global gene expression profiling, are involved in regulation of TNFalpha-induced mPGES-1 and COX-2 expression in gingival fibroblasts. BMC Genomics. 2010 Apr 15;11:241.

Lundin S, Stranneheim H, Pettersson E, Klevebring D, Lundeberg J. Increased throughput by parallelization of library preparation for massive sequencing. PLoS One. 2010 Apr 6;5(4):e10029.

Seidel S, Garvalov BK, Wirta V, von Stechow L, Schänzer A, Meletis K, Wolter M, Sommerlad D, Henze AT, Nistér M, Reifenberger G, Lundeberg J, Frisén J, Acker T. A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha. Brain. 2010 Apr;133(Pt 4):983-95.

Picelli S, Zajac P, Zhou XL, Edler D, Lenander C, Dalén J, Hjern F, Lundqvist N, Lindforss U, Påhlman L, Smedh K, Törnqvist A, Holm J, Janson M, Andersson M, Ekelund S, Olsson L, Lundeberg J, Lindblom A. Common variants in human CRC genes as low-risk alleles. Eur J Cancer. 2010 Apr;46(6):1041-8.

 

March

Arner E, Rydén M, Arner P. Tumor necrosis factor alpha and regulation of adipose tissue. N Engl J Med. 2010 Mar 25;362(12):1151-3.

van Harmelen V, Dicker A, Sjölin E, Blomqvist L, Wirén M, Hoffstedt J, Rydén M, Arner P. Effects of pain controlling neuropeptides on human fat cell lipolysis. Int J Obes (Lond). 2010 Mar 16.

Mejhert N, Galitzky J, Pettersson AT, Bambace C, Blomqvist L, Bouloumié A, Frayn KN, Dahlman I, Arner P, Rydén M. Mapping of the fibroblast growth factors in human white adipose tissue. J Clin Endocrinol Metab. 2010 May;95(5):2451-7. Epub 2010 Mar 12.

Klevebring D, Bjursell M, Emanuelsson O, Lundeberg J. In-depth transcriptome analysis reveals novel TARs and prevalent antisense transcription in human cell lines. PLoS One. 2010 Mar 25;5(3):e9762.

 

February

Grau K, Cauchi S, Holst C, Astrup A, Martinez JA, Saris WH, Blaak EE, Oppert JM, Arner P, Rössner S, Macdonald IA, Klimcakova E, Langin D, Pedersen O, Froguel P, Sørensen TI. TCF7L2 rs7903146-macronutrient interaction in obese individuals' responses to a 10-wk randomized hypoenergetic diet. Am J Clin Nutr. 2010 Feb;91(2):472-9.

Jönsson AK, Hakkarainen KM, Spigset O, Druid H, Hiselius A, Hägg S. Preventable drug related mortality in a Swedish population. Pharmacoepidemiol Drug Saf. 2010 Feb;19(2):211-5.

Sandberg J, Neiman M, Ahmadian A, Lundeberg J. Gene-specific FACS sorting method for target selection in high-throughput amplicon sequencing. BMC Genomics. 2010 Feb 26;11:140.

Nilsson M, Possnert G, Edlund H, Budowle B, Kjellström A, Allen M. Analysis of the putative remains of a European patron saint--St. Birgitta. PLoS One. 2010 Feb 16;5(2):e8986.

January

Pettersson AT, Laurencikiene J, Mejhert N, Näslund E, Bouloumié A, Dahlman I, Arner P, Rydén M. A possible inflammatory role of twist1 in human white adipocytes. Diabetes.

Arner E, Westermark PO, Spalding KL, Britton T, Rydén M, Frisén J, Bernard S, Arner P. Adipocyte turnover: relevance to human adipose tissue morphology. Diabetes. 2010 Jan;59(1):105-9.

 

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Publications 2009

 

December

Pang JF, Kluetsch C, Zou XJ, Zhang AB, Luo LY, Angleby H, Ardalan A, Ekström C, Sköllermo A, Lundeberg J, Matsumura S, Leitner T, Zhang YP, Savolainen P. mtDNA data indicate a single origin for dogs south of Yangtze River, less than 16,300 years ago, from numerous wolves. Mol Biol Evol. 2009 Dec;26(12):2849-64.

Klevebring D, Street NR, Fahlgren N, Kasschau KD, Carrington JC, Lundeberg J, Jansson S. Genome-wide profiling of populus small RNAs. BMC Genomics. 2009 Dec 20;10:620.

Stålman A, Tsai JA, Segerdahl M, Dungner E, Arner P, Felländer-Tsai L. Ketorolac but not morphine exerts inflammatory and metabolic effects in synovial membrane after knee arthroscopy: a double-blind randomized prospective study using the microdialysis technique. Reg Anesth Pain Med. 2009 Nov-Dec;34(6):557-64.

Alkass K, Buchholz BA, Ohtani S, Yamamoto T, Druid H, Spalding KL. Age estimation in forensic sciences: Application of combined aspartic acid racemization and radiocarbon analysis. Mol Cell Proteomics. 2009 Dec 4.

Jönsson AK, Hakkarainen KM, Spigset O, Druid H, Hiselius A, Hägg S. Preventable drug related mortality in a Swedish population. Pharmacoepidemiol Drug Saf. 2009 Dec 8;19(2):211-215.


November

Grau K, Hansen T, Holst C, Astrup A, Saris WH, Arner P, Rössner S, Macdonald I, Polak J, Oppert JM, Langin D, Martinez JA, Pedersen O, Sørensen TI. Macronutrient-specific effect of FTO rs9939609 in response to a 10-week randomized hypo-energetic diet among obese Europeans. Int J Obes (Lond). 2009 Nov;33(11):1227-34.

Genander M, Halford MM, Xu NJ, Eriksson M, Yu Z, Qiu Z, Martling A, Greicius G, Thakar S, Catchpole T, Chumley MJ, Zdunek S, Wang C, Holm T, Goff SP, Pettersson S, Pestell RG, Henkemeyer M, Frisén J. Dissociation of EphB2 signaling pathways mediating progenitor cell proliferation and tumor suppression. Cell. 2009 Nov 13;139(4):679-92.

Pettersson E, Ståhl PL, Mahdessian H, Käller M, Lundeberg J, Ahmadian A. Visual DNA as a diagnostic tool. Electrophoresis. 2009 Nov;30(21):3691-5.


October

Corpeleijn E, Petersen L, Holst C, Saris WH, Astrup A, Langin D, Macdonald I, Martinez JA, Oppert JM, Polak J, Pedersen O, Froguel P, Arner P, Sørensen TI, Blaak EE. Obesity-related Polymorphisms and Their Associations With the Ability to Regulate Fat Oxidation in Obese Europeans: The NUGENOB Study. Obesity (Silver Spring). 2009 Oct 29.

Arner E, Westermark PO, Spalding KL, Britton T, Rydén M, Frisén J, Bernard S, Arner P. ADIPOCYTE TURNOVER: RELEVANCE TO HUMAN ADIPOSE TISSUE MORPHOLOGY. Diabetes. 2009 Oct 21.

Klevebring D, Gry M, Lindberg J, Eidefors A, Lundeberg J. Automation of cDNA synthesis and labelling improves reproducibility. J Biomed Biotechnol. 2009;2009:396808. Epub 2009 Oct 15.

Corpeleijn E, Petersen L, Holst C, Saris WH, Astrup A, Langin D, Macdonald I, Martinez JA, Oppert JM, Polak J, Pedersen O, Froguel P, Arner P, Sørensen TI, Blaak EE. Obesity-related Polymorphisms and Their Associations With the Ability to Regulate Fat Oxidation in Obese Europeans: The NUGENOB Study. Obesity (Silver Spring). 2009 Oct 29.


September

Hou X, Aldahan A, Nielsen SP, Possnert G. Time series of 129I and 127I speciation in precipitation from Denmark. Environ Sci Technol. 2009 Sep 1;43(17):6522-8.

Mash DC, Duque L, Pablo J, Qin Y, Adi N, Hearn WL, Hyma BA, Karch SB, Druid H, Wetli CV. Brain biomarkers for identifying excited delirium as a cause of sudden death. Forensic Sci Int. 2009 Sep 10;190(1-3):e13-9. Epub 2009 Jun 21. PubMed PMID: 19541436.

Lindström S, Eriksson M, Vazin T, Sandberg J, Lundeberg J, Frisén J, Andersson-Svahn H. High-density microwell chip for culture and analysis of stem cells. PLoS One. 2009 Sep 14;4(9):e6997

August

Sell H, Laurencikiene J, Taube A, Eckardt K, Cramer A, Horrighs A, Arner P, Eckel J. Chemerin is a novel adipocyte-derived factor inducing insulin resistance in primary human skeletal muscle cells. Diabetes. 2009 Dec;58(12):2731-40. Epub 2009 Aug 31.

Lindberg J, Lundeberg J. The plasticity of the mammalian transcriptome. Genomics. 2009 Aug 28.

July

Bezaire V, Mairal A, Ribet C, Lefort C, Girousse A, Jocken J, Laurencikiene J, Anesia R, Rodriguez AM, Ryden M, Stenson BM, Dani C, Ailhaud G, Arner P, Langin D. Contribution of Adipose Triglyceride Lipase and Hormone-sensitive Lipase to Lipolysis in hMADS Adipocytes. J Biol Chem. 2009 Jul 3;284(27):18282-91.

Laurell C, Velázquez-Fernández D, Lindsten K, Juhlin C, Enberg U, Geli J, Höög A, Kjellman M, Lundeberg J, Hamberger B, Larsson C, Nilsson P, Bäckdahl M. Transcriptional profiling enables molecular classification of adrenocortical tumours. Eur J Endocrinol. 2009 Jul;161(1):141-52.

Nätt D, Lindqvist N, Stranneheim H, Lundeberg J, Torjesen PA, Jensen P. Inheritance of acquired behaviour adaptations and brain gene expression in chickens. PLoS One. 2009 Jul 28;4(7):e6405. Erratum in: PLoS One. 2009;4(8). doi: 10.1371/annotation/4f90ac09-ae5e-469a-a2f3-21a5ac68dc31. PubMed PMID: 19636381; PubMed Central PMCID: PMC2713434.

June

Goossens GH, Petersen L, Blaak EE, Hul G, Arner P, Astrup A, Froguel P, Patel K, Pedersen O, Polak J, Oppert JM, Martinez JA, Sørensen TI, Saris WH; NUGENOB Consortium. Several obesity- and nutrient-related gene polymorphisms but not FTO and UCP variants modulate postabsorptive resting energy expenditure and fat-induced thermogenesis in obese individuals: the NUGENOB study. Int J Obes (Lond). 2009 Jun;33(6):669-79.

Stenson BM, Rydén M, Steffensen KR, Wåhlén K, Pettersson AT, Jocken JW, Arner P, Laurencikiene J. Activation of liver X receptor (LXR) regulates substrate oxidation in white adipocytes. Endocrinology. 2009 Jun 25.

Mash DC, Duque L, Pablo J, Qin Y, Adi N, Hearn WL, Hyma BA, Karch SB, Druid H, Wetli CV. Brain biomarkers for identifying excited delirium as a cause of sudden death. Forensic Sci Int. 2009 Jun 19.

May

Flanagan JN, Linder K, Mejhert N, Dungner E, Wahlen K, Decaunes P, Rydén M, Björklund P, Arver S, Bhasin S, Bouloumie A, Arner P, Dahlman I. Role of Follistatin in Promoting Adpiogenesis in Women. J Clin Endocrinol Metab. 2009 May 26.

Jernås M, Olsson B, Arner P, Jacobson P, Sjöström L, Walley A, Froguel P, McTernan PG, Hoffstedt J, Carlsson LM. Regulation of carboxylesterase 1 (CES1) in human adipose tissue. Biochem Biophys Res Commun. 2009 May 22;383(1):63-7.

Sandberg J, Ståhl PL, Ahmadian A, Bjursell MK, Lundeberg J. Flow cytometry for enrichment and titration in massively parallel DNA sequencing. Nucleic Acids Res. 2009 May;37(8):e63.

April

Bergmann O, Bhardwaj RD, Bernard S, Zdunek S, Barnabé-Heider F, Walsh S, Zupicich J, Alkass K, Buchholz BA, Druid H, Jovinge S, Frisén J. Evidence for cardiomyocyte renewal in humans. Science. 2009 Apr 3;324(5923):98-102. PubMed PMID: 19342590.

Jönsson AK, Spigset O, Tjäderborn M, Druid H, Hägg S. Fatal drug poisonings in a Swedish general population. BMC Clin Pharmacol. 2009 Apr 27;9:7.

Höiom V, Tuominen R, Käller M, Lindén D, Ahmadian A, Månsson-Brahme E, Egyhazi S, Sjöberg K, Lundeberg J, Hansson J. MC1R variation and melanoma risk in the Swedish population in relation to clinical and pathological parameters. Pigment Cell Melanoma Res. 2009 Apr;22(2):196-204.

March

Carlén M, Meletis K, Göritz C, Darsalia V, Evergren E, Tanigaki K, Amendola M, Barnabé-Heider F, Yeung MS, Naldini L, Honjo T, Kokaia Z, Shupliakov O, Cassidy RM, Lindvall O, Frisén J. Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke. Nat Neurosci. 2009 Mar;12(3):259-67. Epub 2009 Feb 22.

Salehpour M, Forsgard N, Possnert G. FemtoMolar measurements using accelerator mass spectrometry. Rapid Commun Mass Spectrom. 2009 Mar;23(5):557-63. PMID: 19177507

Zilg B, Alkass K, Berg S, Druid H. Postmortem identification of hyperglycemia. Forensic Sci Int. 2009 Mar 10;185(1-3):89-95. Epub 2009 Jan 23. PMID: 19167848

Jernås M, Olsson B, Arner P, Jacobson P, Sjöström L, Walley A, Froguel P, McTernan PG, Hoffstedt J, Carlsson LM. Regulation of carboxylesterase 1 (CES1) in human adipose tissue. Biochem Biophys Res Commun. 2009 Mar 28. [Epub ahead of print] PubMed PMID: 19332024.

Sultan A, Strodthoff D, Robertson AK, Berne GP, Fauconnier J, Parini P, Rydén M, Thierry-Mieg N, Johansson ME, Chibalin AV, Zierath JR, Arner P, Hansson GK. T Cell-Mediated Inflammation in Adipose Tissue Does Not Cause Insulin Resistance in Hyperlipidemic Mice. Circ Res. 2009 Mar 19. [Epub ahead of print] PubMed PMID: 19299644.

February

Dicker A, Aström G, Wåhlén K, Hoffstedt J, Näslund E, Wirén M, Rydén M, Arner P, Harmelen VV. Primary Differences in Lipolysis between Human Omental and Subcutaneous Adipose Tissue Observed Using In Vitro Differentiated Adipocytes. Horm Metab Res. 2009 Feb 9. [Epub ahead of print] PMID: 19204889

Pettersson E, Lundeberg J, Ahmadian A. Generations of sequencing technologies. Genomics. 2009 Feb;93(2):105-11.

 

January

Hou X, Hansen V, Aldahan A, Possnert G, Lind OC, Lujaniene G. A review on speciation of iodine-129 in the environmental and biological samples. Anal Chim Acta. 2009 Jan 26;632(2):181-96. Epub 2008 Nov 17. Review. PMID: 19110092

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Publications 2008

December

Englund E, Aldahan A, Possnert G, Haltia-Hovi E, Hou X, Renberg I, Saarinen T. Modeling fallout of anthropogenic 129I. Environ Sci Technol. 2008 Dec 15;42(24):9225-30. PMID: 19174896

Salehpour M, Forsgard N, Possnert G. Accelerator mass spectrometry of small biological samples. Rapid Commun Mass Spectrom. 2008 Dec;22(23):3928-34

van Hees AM, Saris WH, Dallinga-Thie GM, Hul GB, Martinez JA, Oppert JM, Stich V, Astrup A, Arner P, Sørensen TI, Blaak EE. Fasting and postprandial remnant-like particle cholesterol concentrations in obese participants are associated with plasma triglycerides, insulin resistance, and body fat distribution. J Nutr. 2008 Dec;138(12):2399-405.

November

Skogsberg J, Dicker A, Rydén M, Aström G, Nilsson R, Bhuiyan H, Vitols S, Mairal A, Langin D, Alberts P, Walum E, Tegnér J, Hamsten A, Arner P, Björkegren J. ApoB100-LDL acts as a metabolic signal from liver to peripheral fat causing inhibition of lipolysis in adipocytes. PLoS ONE. 2008;3(11):e3771. Epub 2008 Nov 20.

Laurencikiene J, Stenson BM, Arvidsson Nordström E, Agustsson T, Langin D, Isaksson B, Permert J, Rydén M, Arner P. Evidence for an important role of CIDEA in human cancer cachexia. Cancer Res. 2008 Nov 15;68(22):9247-54.

October

Yumoto N, Wakatsuki S, Kurisaki T, Hara Y, Osumi N, Frisén J, Sehara-Fujisawa A. Meltrin beta/ADAM19 interacting with EphA4 in developing neural cells participates in formation of the neuromuscular junction. PLoS ONE. 2008 Oct 2;3(10)

Passante L, Gaspard N, Degraeve M, Frisén J, Kullander K, De Maertelaer V, Vanderhaeghen P. Temporal regulation of ephrin/Eph signalling is required for the spatial patterning of the mammalian striatum. Development. 2008 Oct;135(19)

Duinsbergen D, Eriksson M, 't Hoen PA, Frisén J, Mikkers H. Induced pluripotency with endogenous and inducible genes. Exp Cell Res. 2008 Oct 15;314(17)

Rydén M, Agustsson T, Laurencikiene J, Britton T, Sjölin E, Isaksson B, Permert J, Arner P. Lipolysis--not inflammation, cell death, or lipogenesis--is involved in adipose tissue loss in cancer cachexia. Cancer. 2008 Oct 1;113(7):1695-704.

September

Capel F, Viguerie N, Vega N, Dejean S, Arner P, Klimcakova E, Martinez A, Saris WH, Holst C, Taylor M, Oppert JM, Sørensen TI, Clément K, Vidal H, Langin D. Contribution of Energy Restriction and Macronutrient Composition to Changes in Adipose Tissue Gene Expression during Dietary Weight-Loss Programs in Obese Women. J Clin Endocrinol Metab. 2008 Sep 9.

Englund E, Aldahan A, Possnert G. Tracing anthropogenic nuclear activity with (129)I in lake sediment. J Environ Radioact. 2008;99(2):219-29. Epub 2007 Sep 24.

August

Salehpour M, Possnert G, Bryhni H, Palminger-Hallén I, Ståhle L. Biological accelerator mass spectrometry at Uppsala University. Appl Radiat Isot. 2008 Aug 6.

July

Meletis K, Barnabé-Heider F, Carlén M, Evergren E, Tomilin N, Shupliakov O, Frisén J. Spinal cord injury reveals multilineage differentiation of ependymal cells. PLoS Biol. 2008 Jul 22;6(7)

Barnabé-Heider F, Frisén J. Stem cells for spinal cord repair. Cell Stem Cell. 2008 Jul 3;3(1):16-24. Review.

June

Spalding KL, Arner E, Westermark PO, Bernard S, Buchholz BA, Bergmann O, Blomqvist L, Hoffstedt J, Näslund E, Britton T, Concha H, Hassan M, Rydén M, Frisén J, Arner P. Dynamics of fat cell turnover in humans. Nature. 2008 Jun 5;453(7196):783-7.

Arner P, Stenson BM, Dungner E, Näslund E, Hoffstedt J, Ryden M, Dahlman I. Expression of six transmembrane protein of prostate 2 in human adipose tissue associates with adiposity and insulin resistance. J Clin Endocrinol Metab. 2008 Jun;93(6):2249-54.

Reis M, Aamo T, Ahlner J, Druid H. Reference concentrations of antidepressants. A compilation of postmortem and therapeutic levels. J Anal Toxicol. 2007 Jun;31(5):254-64.

May

Arner P, Pettersson A, Mitchell PJ, Dunbar JD, Kharitonenkov A, Rydén M. FGF21 attenuates lipolysis in human adipocytes - a possible link to improved insulin sensitivity. FEBS Lett. 2008 May 28;582(12):1725-30. Epub 2008 May 5.

Stålman A, Tsai JA, Wredmark T, Dungner E, Arner P, Felländer-Tsai L. Local inflammatory and metabolic response in the knee synovium after arthroscopy or arthroscopic anterior cruciate ligament reconstruction. Arthroscopy. 2008 May;24(5):579-84.

Jiao H, Kaaman M, Dungner E, Kere J, Arner P, Dahlman I. Association analysis of positional obesity candidate genes based on integrated data from transcriptomics and linkage analysis. Int J Obes (Lond). 2008 May;32(5):816-25.

Salehpour M, Possnert G, Bryhni H. Subattomole sensitivity in biological accelerator mass spectrometry. Anal Chem. 2008 May 15;80(10):3515-21.

April

Wester K, Jönsson AK, Spigset O, Druid H, Hägg S. Incidence of fatal adverse drug reactions: a population based study. Br J Clin Pharmacol. 2008 Apr;65(4):573-9. Epub 2007 Dec 7.

March

Lång P, van Harmelen V, Rydén M, Kaaman M, Parini P, Carneheim C, Cassady AI, Hume DA, Andersson G, Arner P. Monomeric tartrate resistant acid phosphatase induces insulin sensitive obesity. PLoS ONE. 2008 Mar 5;3(3):e1713.

Feb

Barnabé-Heider F, Meletis K, Eriksson M, Bergmann O, Sabelström H, Harvey MA, Mikkers H, Frisén J. Genetic manipulation of adult mouse neurogenic niches by in vivo electroporation. Nat Methods. 2008 Feb;5(2):189-96.

January

Rainio J, De Paoli G, Druid H, Kauppila R, De Giorgio F, Bortolotti F, Tagliaro F. Post-mortem stability and redistribution of carbohydrate-deficient transferrin (CDT). Forensic Sci Int. 2008 Jan 30;174(2-3):161-5.

Kvarnstrand L, Milsom I, Lekander T, Druid H, Jacobsson B. Maternal fatalities, fetal and neonatal deaths related to motor vehicle crashes during pregnancy: a national population-based study. Acta Obstet Gynecol Scand. 2008;87(9):946-52.